To prevent Windows from creating multiple instances of your Dymo printer plug the printer into the same USB port all the time. Using different ports can cause Windows to recognize the printer as a new device, resulting in the creation of duplicate printer entries.

 

Possibly to fix this issue, please follow the steps below:

Go to Control Panel > Devices and Printers.

Right-click on any duplicate printers (e.g., "Dymo LabelWriter 550 (Copy 1)").

Select Remove device.

Repeat for all duplicate printers.